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EFFECT OF AQEUOUS STEM BARK EXTRACT OF VITELLARIA PARADOXA ON IFN-γ and IL-4 LEVELS IN ALBINO RATS

Mustapha Umar Kalgo, Kabir Magaji Hamid, Yazeed Garba Bala, Usman Abubakar, Abubakar Babangida Usman, Adamu Muhammad Ibrahim

Vitellaria paradoxa is a well-known plant of Africa origin whose leaves, roots, and stem bark extract have been used for treatment of various ailments. Cytokines are small, non-structural proteins with...

May 14, 2025 367 views Issue 2

Remedial Effect of Mormodica Charantia on Hepatic Inflammation and Oxidative Stress Induced by Carbon Tetrachloride in Wistar Rats

Bini N, Osadolor HB, Elekofehinti OO, Dic-Ijiewere EO

Background: Anti-inflammatory and antioxidant properties of Mormodica charantia has been a crucial factor in reducing liver damage. The medicinal value of M. charantia is derived from its bioactive components, which...

May 14, 2025 238 views Issue 1

Resistance Pattern of Tuberculosis Before and During COVID-19 Era in Nigeria: A Systematic Review

Adetomi Bademosi, Nnenna Ihua, Chidinma Judith Opara, Golda Lugesi Ezeh, Paago Anthony N., Felix Eedee Konne

Background: Tuberculosis (TB), one of the leading infectious diseases of global health concern has drawn the attention of researchers towards investigating the trends of the infection, its resistance and associated...

May 14, 2025 604 views Issue 2

Environmental Risk Factors of Helicobacter pylori Infection Among Dyspeptic Patients at Rivers State University Teaching Hospital (RSUTH): A Cross-Sectional Study

Kingsley Okpara, Edwin Isotu Edeh and Theresa Thompson

Helicobacter pylori (H. pylori) is a significant global health concern, linked to chronic gastritis, peptic ulcers, and gastric cancer. This study aimed to determine the prevalence of H. pylori infection...

Mar 08, 2025 468 views Issue 1

EVALUATION OF INFLAMMATORY CYTOKINES IN COVID-19 PATIENTS AT RIVERS STATE UNIVERSITY TEACHING HOSPITAL, NIGERIA

Kingsley Ezechukwu Okpara, Queen Elechi, Chikadibia Fyneface Amadi, and Nnana Onyekwere

The COVID-19 pandemic has highlighted the critical role of inflammatory cytokines in the disease's pathophysiology and outcomes. This study aimed to assess the serum levels of key inflammatory cytokines—IL-1β, IL-6,...

Mar 08, 2025 885 views Issue 1

Effect of Gravidity on Biochemical Parameters in Normotensives and Hypertensive 2nd Trimester Pregnant Women

Tomaziga Tomiloba Oladapo-Akinfolarin ,,,and Ebirien-Agana Samuel Bartimaeus

The study was aimed at evaluating the effect of gravidity on selected biochemical parameters of cardiovascular disease in normotensive and hypertensive 2nd trimester pregnant women attending antenatal clinics at Rivers...

Mar 08, 2025 354 views Issue 1

Changes in Liver and renal function of Subjects infected with corona Virus 19 (COVID 19) on Zinc and Vitamin C in a Health care facility in Southern Nigeria

Ibitoroko Maureen George-Opuda, and Adebayo Olugbenga Adegoke

The COVID-19 outbreak by the new coronavirus strain was recognized as a pandemic by the World Health Organization (WHO). ). Vitamin C is a water soluble antioxidant vitamin. Zinc is...

Jan 05, 2025 400 views Issue 6

Effect of oral administration of honey on Liver function parameters of albino rats treated with Dichlorvos (sniper)

Ibitoroko Maureen George-Opuda, Favour Emeji

Background and aim: Dichlorvos, also known as DDVP (2,2-dichlorovinyl dimethyl phosphate) is an organophosphate insecticide cum pesticide. This study is to determine the effect of oral administration of honey on...

Jan 05, 2025 479 views Issue 6

OESOPHAGEAL DENTURE IMPACTION: A CASE PRESENTATION

Chinedu Joseph Okonkwo, Arinze Raphael Onyekwelu, and Chinonso Hillary Agwara

BACKGROUND:Otolaryngologists frequently face challenges of impacted oesophageal dentures in our environment. This study focuses on a 31-year old bricklayer with impacted denture in the oesophagus in our centre.CASE PRESENTATION:This case,...

Jan 05, 2025 428 views Issue 6

Lifesaving Impact and Effectiveness of Sustainable Livelihood Interventions in Emergency Situations: A Multi-Sectoral Analysis of Humanitarian Response in Nigeria

Saidu Malgwi HASSAN, Ernest Chinedu OKOLI, Nelyn Akunna OKOYE and Kelechi Nelson ADINDU

AbstractBackground: Sustainable Livelihood Interventions (SLIs) have been integral in addressing both short-term needs and long-term resilience in Nigeria’s multifaceted emergencies. This systematic review aims to evaluate the impact and effectiveness...

Nov 27, 2024 543 views Issue 5