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Comparison of Factor 8 (VIII) and fibrinogen Viability in Whole Blood and Fresh Frozen Plasma

Nwika Goodnews Nkabari, Ransom Baribefii Jacob, Beatrice W.Moore-Igwe

Background and aim: Blood transfusion plays a critical role in modern medicine, ensuring the availability of safe and viable blood products for patients in need. In a special medical condition...

Jan 15, 2026 52 views Issue 6

Caspase-1 as a Biomarker of Metabolic and Inflammatory Toxicity in Type 2 Diabetes Mellitus

Ibitoroko M. George-Opuda, Sheudeen A. Abubakar, and Ojoye N. Briggs

Background: Persistent hyperglycemia and lipid imbalance in diabetes contribute to both metabolic and inflammatory toxicity. Caspase-1, a central component of the inflammasome, mediates pyroptosis and the maturation of pro-inflammatory cytokines....

Jan 13, 2026 55 views Issue 6

Physician-led mental health interventions to reduce opioid related mortality and morbidity in underserved populations in the US

Obianuju Mirian Akujuobi, Jude Chuks Azu, Zona Uzoigwe, Okoye Nelyn Akunna

AbstractBackground: Opioid - related morbidity and mortality disproportionately affect underserved populations in the United States, reflecting gaps in access to coordinated mental health and substance use care. While integrated care...

Jan 11, 2026 51 views Issue 6

Association between Socio-demographic Factors and the rate of Helicobacter pylori infection across various diagnostic techniques among patients in Rivers State, Port Harcourt, Nigeria

Buduka Blessing Meshack, Nwokah Easter, Enoch Smart Amala

Background: In 2015, an estimated 50% of the world’s population had Helicobacter pylori in their upper gastrointestinal tracts. Although Helicobacter pylori infection usually shows no symptoms, it has been regularly...

Oct 14, 2025 106 views Issue 2

TOXOPLASMOSIS ASSOCIATION WITH PSYCHOSIS

Evelyn Orevaoghene Onosakponome, Ibiso Bruce, Godspower Ikechi Achi

The potential link between Toxoplasma gondii infection and psychosis—particularly schizophrenia and bipolar disorder—has become a central focus of interdisciplinary research spanning psychiatry, neurology, immunology, and infectious disease. Findings from epidemiological...

Sep 06, 2025 221 views Issue 4

Assessment of Chronic Inhalation Exposure Effects of Dichlorvos (Dichlorvos) on Cardioprotective and Atherogenic Indices in the Blood of New Zealand White Rabbits

C.C. Ozoemena.

Background: Dichlorvos, a widely used organophosphate pesticide, is frequently applied in agricultural and domestic settings. Its high volatility makes inhalation a common route of exposure, raising concerns about its chronic...

Sep 02, 2025 147 views Issue 4

Toxicological Effects of 2-2, Dichlorovinyl Dimethyl Phosphate on Lipid and Glucose Levels in the Blood of New Zealand White Rabbits by Inhalation Route of Administration

C.C. Ozoemena

Background: Dichlorvos, a widely used organophosphate pesticide, is known for its acute cholinergic toxicity, but less is understood about its chronic metabolic effects. This study investigated the impact of prolonged...

Sep 02, 2025 155 views Issue 4

Mucocutaneous Leishmaniasis: A Comprehensive Review of Epidemiology, Pathogenesis, Diagnosis, and Control Strategies

RoseMary Kaiso Esiere, Erasmus Martha A, Itek Robinson Ndifrekeabasi, George Affia Aniekan

Mucocutaneous leishmaniasis (MCL) is a neglected tropical disease caused by Leishmania species, primarily affecting the mucosal and cutaneous tissues of the oral, nasal, and pharyngeal regions. Transmitted through the bite...

Jul 17, 2025 323 views Issue 3

The Effect of Parity on Atherogenic Indices in Hypertensive Pregnant Women at 2nd Trimester

Tomaziga Tomiloba Oladapo-Akinfolarin, Oladapo Mayowa Akinfolarin

Dyslipidemia, or abnormal lipid metabolism, is a major triggering factor in atherosclerosis aggravated by hypertension. In this study, 100 female participants were chosen at random from Rivers State University and...

Jul 17, 2025 176 views Issue 3

Evaluation of the Parasitic Contamination of Vegetables from Farms and Markets in Owerri, Imo State

Kingsley Okpara, Godspower Ikechi Achi, Erasmus Martha A, Sarah Israel Obey-Nke

This study was carried out to evaluate the parasitic contamination of vegetables from some selected farms and markets in Owerri, Imo State. A total of 100 samples of vegetables were...

Jul 09, 2025 227 views Issue 3