Background: D- dimer is a protein fragment formed when a blood clot is been dissolved in the body. It is associated with coagulation, which further play a role in the formation of thrombo-emboli.
Aim: To assess D-Dimer levels as a potential risk for thrombo-embolism in patients diagnosed with monkeypox virus
Methodology: The study which was conducted at Federal Medical Centre, Owerri, Imo State involved 23 participants presenting with various medical conditions, including skin issues and associated symptoms like fever, chills, and sexually transmitted infections. Samples collected between May 1 and 31, 2022, underwent immunoassay and dermatologic tests, adhering to strict infection prevention guidelines. Out of 23 samples, 14 tested positive for the virus, forming the basis for analysis and discussion.
Result: The examined socio-demographic characteristics and clinical presentations of 14 participants, with majority aged 21-30 (57.1%), male (57.1%), predominantly students (42.9%). Most experienced symptoms for 1-10 days (64.3%), and high D-dimer concentrations were noted in 92.9% of patients. Medication usage included antibiotics (92.9%) and various combinations of vitamins, anti-histamines, and zinc. Hospitalization was common (85.7%), primarily for 1-10 days, with a favorable treatment outcome (92.9%)
Conclusion: This study observed significant increase in the plasma concentration of D-dimer, which is dangerous due to its associated risk with thrombo-embolism.